6000SF*Sleeps24*WalknDine*YardOasis*Firepit*HotTub*Dome*Pets*Lux Amenities*Views | House in Jeffersonville
8 Bedroom House in Jeffersonville
*** Deaconess Guesthouse — Iconic Luxury Overlooking the Ohio River · Minutes from Louisville and Historic Jeffersonville ***
★ Where Historic Architecture Meets Modern Luxury
Deaconess Guesthouse is an extraordinary 1800s landmark estate, originally Jeffersonville’s first public hospital and now meticulously reimagined as a premier riverfront retreat. Restored by Charming Vacation Homes with a focus on craftsmanship, comfort and timeless elegance, this distinguished property blends historic character with boutique-hotel sophistication—all framed by expansive Ohio River views.
Situated just steps from Jeffersonville’s lively riverfront district and minutes from Downtown Louisville and the Bourbon Trail, the estate offers an exceptional setting for guests seeking a stay defined by luxury, convenience and unforgettable surroundings.
★ Designed for Elevated Gatherings and Exceptional Stays
Offering 8 designer bedrooms and 6 spa-inspired bathrooms across four private suites, Deaconess Guesthouse accommodates up to 24 guests—ideal for:
- Corporate and executive retreats
- Multi-family vacations
- Wedding parties and milestone celebrations
- Holiday gatherings and special events
Every room is curated with refined textures, custom artwork, premium furnishings and warm, inviting spaces designed for conversation, connection and relaxation.
★ Signature Features and Luxury Amenities
1. Private Hot Tub and Fire Pit: A serene riverfront escape perfect for unwinding under open skies.
2. Wraparound Porches and Balconies: Enjoy sweeping water views, morning sunrises, and sunset cocktails.
3. Stargazing Dome: A unique retreat for children, creatives, and couples looking for an imaginative hideaway.
4. Ample On-Site Parking: A rare luxury for large groups, corporate stays, and event planners.
5. Unmatched Location with Premier Access
6. Walkable to Downtown Jeffersonville: Boutique shopping, dining, festivals, and seasonal waterfront events.
7. 2.5 Miles to Downtown Louisville: Distilleries, Churchill Downs, museums, concert venues, sports arenas and vibrant nightlife.
8. Outdoor Recreation: Paddleboarding, biking paths, and scenic riverfront activities right outside the property.
★ An Exceptional Riverfront Estate for Memorable Gatherings
From evenings by the fire pit to shared moments on the wraparound porch as riverboats drift by, Deaconess Guesthouse provides an atmosphere designed for slowing down, savoring your surroundings, and reconnecting with the people who matter most.
Blending historic charm, modern sophistication, and an unrivaled waterfront setting, this estate offers more than a place to stay—it offers an experience, a gathering place, and a setting where unforgettable memories are made.
★ Now Booking Luxury Stays and Private Events
Ideal for:
- Executive and team retreats
- Multi-family vacations
- Weddings, anniversaries, and milestone celebrations
- Holiday gatherings and weekend escapes
Reserve your stay at one of the region’s premier luxury estates—where history, elegance, and meaningful experiences come together.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Breathtaking Panoramic Views: Wake up to sweeping, cinematic vistas of the Ohio River—where each sunrise paints a new masterpiece. Enjoy effortless access to the vibrant downtowns of Jeffersonville and Louisville, offering boutique shopping, award-winning dining, live entertainment and year-round festivals just moments away.
★ Historic Grandeur, Modern Sophistication: This iconic landmark has been meticulously restored and thoughtfully reimagined. Timeless architecture blends seamlessly with contemporary elegance—designer décor, curated furnishings and preserved historic details create a space that feels both luxurious and unmistakably welcoming.
★ Relax in Serene Outdoor Retreats: Savor morning coffee or evening cocktails on covered porches and private balconies overlooking the shimmering river. Each outdoor space is purposefully crafted to capture the tranquility and beauty of waterfront living.
★ Crafted for Connection & Comfort: With 8 beautifully appointed bedrooms and 6 spa-inspired bathrooms, the home delivers exceptional comfort for families, friends and group gatherings. Sunlit living rooms, cozy lounges and spacious gathering areas invite conversation, connection and unforgettable shared moments.
★ Elevated Culinary Experiences: Four fully equipped gourmet kitchens—complete with premium appliances and chef-ready layouts—make celebrations, family meals or private-chef dining experiences effortless and extraordinary.
★ Thoughtful for Families & Pets: Cozy reading corners, kid-friendly spaces and pet-ready amenities ensure every guest—big, small or four-legged—feels right at home.
★ Your Private Outdoor Oasis: Unwind in the hot tub, gather around the riverfront fire pit, dine under the gazebo or Hyperdome, or enjoy lawn games beneath the stars. Each outdoor feature is intentionally designed to refresh, reconnect and elevate your stay.
★ Endless Entertainment: Multiple lounge areas, Smart Roku TVs, indoor and outdoor games provide countless ways to relax, play and enjoy your time together.
★ Perfect for Groups, Retreats & Celebrations: Ideal for family reunions, corporate retreats, milestone events or extended getaways. Enjoy abundant parking, four washer/dryer sets and flexible indoor/outdoor spaces tailored for hosting memorable gatherings.
★ A Signature Riverfront Experience Awaits
Discover the perfect fusion of historic charm, elevated comfort and an unbeatable riverfront location—where the beauty of the Ohio River sets the stage for an unforgettable stay, and every visit becomes a cherished part of your story.
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) ** STRICT CANCELLATION for DERBY/ Bourbon & Beyond **
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU!!
6000SF*Sleeps24*WalknDine*YardOasis*Firepit*HotTub*Dome*Pets*Lux Amenities*Views is located in Jeffersonville. 6000SF*Sleeps24*WalknDine*YardOasis*Firepit*HotTub*Dome*Pets*Lux Amenities*Views provides accommodation, featuring Fireplace/Heating, Hot Tub, Laundry, among other amenities. This House features Fireplace/Heating, Hot Tub, Laundry, to make your stay a comfortable one.
6000SF*Sleeps24*WalknDine*YardOasis*Firepit*HotTub*Dome*Pets*Lux Amenities*Views has 8 Bedrooms , 6 Bathrooms, and max occupancy of 24 people. The minimum rental for this property is 1 nights, but this can change depending on the season you plan on staying. Previous guests have rated it 2, and VRBO labeled it a top-rated House because of the excellent services rendered by the owner or manager of this House, and has consistently provided great experiences for their guests. Most families or guests that use it recommend it to their friends and some of them are repeat guests. House has a friendly neighborhood, and the Jeffersonville has interesting places to visit. If you want to learn more about the House in Jeffersonville, such as places to visit and things to do nearby, you can check below to learn more.
This Property is OneKey Eligible
Earn OneKeyCash for every dollar spent on eligible vacation rentals, villas, cottages, cabins, and more when you book on Vrbo.
Amenities
Facility Overview
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Air conditioning
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Heating
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Bathtub or shower
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Hair dryer
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Towels provided
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6 bathrooms
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8 bedrooms
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Bed sheets provided
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Sofa bed
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Dining table
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Living room
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Fireplace
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Kitchen island
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Refrigerator
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Stovetop
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Dishwasher
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Coffee/tea maker
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Oven
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Toaster
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Microwave
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Cookware/dishes/utensils
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Laundry facilities
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Washing machine and dryer
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Near laundromat
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Onsite parking
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Car recommended
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Pet friendly
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Hardwood flooring in public areas
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Well-lit path to entrance
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Handrails in hallways
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If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
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Handrails in stairways
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Thin carpet in public areas
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Smooth flooring in public areas
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Smoke-free property
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Area rugs in public areas
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Tile flooring in public areas
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Fitness facilities nearby
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Golf nearby
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Kayaking nearby
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Water park
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Winery tours nearby
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Casino nearby
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Marina nearby
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Theme parks nearby
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Fishing nearby
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Power boating nearby
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Games
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Books
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Arcade/game room
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Smart TV
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At least 80% lighting from LEDs
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Recycling
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Water-efficient toilets only
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Water-efficient showers only
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Unit size: 5800 sq ft (539 sq m)
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English
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On the waterfront
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Near a hospital
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Near a zoo
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In the city center
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On the river
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Desk
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Desk chair
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Playground
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Highchair
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Travel crib
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Children's dinnerware
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Iron/ironing board
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Free WiFi
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Balcony
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Firepit
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Barbecue grill
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Fenced yard
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Garden
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First aid kit
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Smoke detector installed (host has indicated there is a smoke detector on the property)
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Carbon monoxide detector installed (host has indicated there is a carbon monoxide detector on the property)
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Deadbolt lock
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Fire extinguisher
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Hot tub
Policies
Extra-person charges may apply and vary depending on property policy government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges host has indicated there is a carbon monoxide detector on the property host has indicated there is a smoke detector on the property onsite parties or group events are strictly prohibited safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed this property is managed through our partner, vrbo. you will receive an email from vrbo with a link to a vrbo account, where you can change or cancel your reservation
Reviews
